Computer hardware setup/updates

I have a GTX 1080 GPU and an 250G solid state hard drive (the one that windows is installed on), I also have a 1TB hard drive available as the D drive. I work a lot on sculpting in VR with Oculus medium (which is like sculpting in Blender or zbrush but in VR and working in 3D space in front of you).  Often, I will get a notification saying "windows is running low on memory..." yet, my PC is not very low on memory (23gigs available). Someone suggested that it could be referring to RAM, since the Oculus tends to take a lot of that and medium is a fairly complex app.

What could I change or update to possibly remedy this issue? We thought of moving everything to the TB hard drive, but since the one everything is already on isn't near full and is faster than the TB hard drive, that doesn't make much sense as the fix. I included a screen-grab of the System details on the PC for anything I missed.
Any ideas or advice would be greatly appreciated!

-Tiff